Sept. 9, 2021 Dear Friends: The Post-Finasteride Syndrome Foundation, represented by consumer rights advocacy group Public Citizen, yesterday filed a lawsuit in Washington, DC, federal court compelling the US Food and Drug Administration to act on our Citizen Petition. Facts laid out in the eight-page complaint include: The “most serious risk of 1 mg finasteride […]
Aug. 4, 2021 Dear Friends: For several years now, our patient manager, Philip Roberts, has been telling me he feels like Radar O’Reilly on M*A*S*H. Fans of the dark Korean War comedy will recall that often after endless hours of stitching up battlefield casualties—and having just flopped onto their cots—the doctors would be interrupted by […]
Aug. 4, 2020 Dear Friends: Back in March, when COVID-19 first swept America, our patient manager was chatting with a thirtysomething patient who’s been suffering from PFS since 2010. Let’s call him Andrew. Andrew had recently run into a colleague from the last full-time job Andrew held before developing the condition and being forced to […]
Symptomatic finasteride users had “significantly lower International Index of Erectile Function composite score” and “significantly lower scores for each of its domains of erectile function, sexual desire, orgasmic function, intercourse satisfaction, and overall satisfaction”… There exists “a significant positive correlation between a subset of Beck Depression Inventory scores related to negative attitude and blood oxygen […]
Aug. 4, 2019 Dear Friends: Irrefutable. It’s a word we’re aiming to make synonymous with PFS by August 2022, when this foundation turns 10. That leaves us just 41 months. But if recent activity on the research and regulatory fronts are any indication—to say nothing of the surge in efforts by patients and their loved […]
The levels of some neuroactive steroids analyzed in CSF of PFS patients were significantly different versus those in healthy controls. In particular, the levels of PREG, as well as of its further metabolites, PROG and DHP, were significantly decreased in CSF of PFS patients. PFS patients show altered levels of important physiological regulators of brain […]
July 20, 2019 Dear Friends: Phase III of the PFS Foundation-sponsored research at the University of Milano (UniMi), which was designed to “study whether epigenetic modifications occur in PFS patients,” has successfully demonstrated epigenetic modifications in PFS patients. Titled Altered methylation pattern of the SRD5A2 gene in cerebrospinal fluid of post-Finasteride patients, the pilot study […]
Background: There is a robust literature in rodents, but not in humans, on the interaction between finasteride and alcohol, particularly as it relates to neurosteroids. Finasteride has been shown to reduce alcohol intake and suppress alcohol preference in male mice. This study examines the role of finasteride in alcohol consumption in humans with male pattern […]
June 5, 2019 Dear Friends: PFS naysayers’ days may be numbered. According to new research in the world’s most influential dermatology journal, medical science is leaning further toward the conclusion that finasteride can cause sexual dysfunction in men taking a 1-mg dose for hair loss. The paper, titled Sexual dysfunction in men taking systemic dermatologic […]
May 30, 2019 Dear Friends: If PFS awareness is what it takes to unite Germany and France, so be it. Last week brought a slew of media coverage out of Deutschland that closely mirrors what we saw a month earlier in the French Republic. The awareness assault began May 21 with a report on the […]