February 20, 2020 Dear Friends: “Clinicians should be aware that men under the age of 40 who use finasteride for alopecia are at risk for suicide if they develop persistent sexual adverse effects and insomnia.” That, according to new research by Michael S. Irwig, MD, attending endocrinologist at Beth Israel Deaconess Medical Center in Boston, […]
October 21, 2019 Dear Friends: PFS awareness took an enormous leap forward today—over the Great Wall and into the Sleeping Giant. At the stroke of midnight, we unveiled a Mandarin Chinese version of our website so that speakers of the world’s second most popular language can learn all about the condition (known to them as […]
Sept. 16, 2019 Dear Friends: Dan Levine, an investigative journalist with the largest news agency in the Western world, last week published a 3,900-word investigative report headlined Court let Merck hide secrets about a popular drug’s risks. A year in the making, the Reuters story uncovered testimony by former Merck executives in the US Propecia […]
Symptomatic finasteride users had “significantly lower International Index of Erectile Function composite score” and “significantly lower scores for each of its domains of erectile function, sexual desire, orgasmic function, intercourse satisfaction, and overall satisfaction”… There exists “a significant positive correlation between a subset of Beck Depression Inventory scores related to negative attitude and blood oxygen […]
Aug. 17, 2019 Dear Friends: The Boot has begun kicking Propecia. Last week, Italian health and lifestyle magazine Starbene, which boasts a weekly circulation of 350,000, ran a story on PFS that begins: The entire world, including Italy, is experiencing a tragedy that requires our attention. It’s that of men, often young, who in hopes […]
Aug. 4, 2019 Dear Friends: Irrefutable. It’s a word we’re aiming to make synonymous with PFS by August 2022, when this foundation turns 10. That leaves us just 41 months. But if recent activity on the research and regulatory fronts are any indication—to say nothing of the surge in efforts by patients and their loved […]
The levels of some neuroactive steroids analyzed in CSF of PFS patients were significantly different versus those in healthy controls. In particular, the levels of PREG, as well as of its further metabolites, PROG and DHP, were significantly decreased in CSF of PFS patients. PFS patients show altered levels of important physiological regulators of brain […]
Background: There is a robust literature in rodents, but not in humans, on the interaction between finasteride and alcohol, particularly as it relates to neurosteroids. Finasteride has been shown to reduce alcohol intake and suppress alcohol preference in male mice. This study examines the role of finasteride in alcohol consumption in humans with male pattern […]
July 28, 2018 Dear Friends: Canada has taken an important first step toward keeping its citizens apprised of finasteride’s many potentially serious and persistent side effects. In the June edition of its Health Product InfoWatch, Health Canada (Canada’s version of the US Food and Drug Administration) reported that “New information regarding the risk of muscle-related […]
SOMERSET, N.J., Jan. 5, 2016 – Reports of finasteride-induced Suicidal and Self-Injurious Behavior are up 33 percent in the World Health Organization Progamme for International Drug Monitoring’s database of adverse drug reactions (ADRs) for Q4 vs. Q3 2015. Within that category (itself a subcategory of Psychiatric Disorders), suicidal ideaton is up 47.2%; suicide attempts up […]