The Post-Finasteride Syndrome Foundation is dedicated to helping fund research on the characterization, underlying biologic mechanisms and treatments of the post-finasteride syndrome (PFS). A secondary goal is to help increase public awareness of PFS.
Often life-altering, PFS is characterized by devastating sexual, neurological, and physical side effects that persist in men who have taken the 5-alpha reductase type II enzyme inhibitor finasteride.
Among the most common finasteride side effects being reported to health agencies are loss of libido, erectile dysfunction, orgasm disorders, depression, Peyronie’s disease and abnormal breast enlargement. Unfortunately for some men, such side effects can persist for months or even years after stopping the drug. [more...]
The PFS Foundation’s primary objective is to help establish medical consensus and acceptance of PFS by promoting scientific and clinical research. Research initiatives focus on uncovering underlying biologic mechanisms for the syndrome and its persistent side effects at a molecular level. [more...]
As media awareness and scientific interest in PFS continues to grow, the PFS Foundation will serve as a central resource for published research on the condition. We aim to facilitate collaborative efforts amongst health care professionals and leading scientists worldwide. [more...]
PFS in the News
Our research definitely concludes that PFS is real. For a subset of these men, the damage persists — maybe forever — even after they go off the drug. We don’t fully understand why, but it is as if something shuts off biologically, and stays that way.
We are becoming more and more aware of persistent sexual health problems occurring as a result of the use of 5-alpha reductase inhibitors, finasteride, and dutasteride, in a subset of patients. What is even more alarming is that in addition to persistent sexual issues, there are persistent central cognitive issues and concerns of persistent depression.