The problem may be rooted in a failure of the central nervous system’s control over sexual function, and not merely in a compromised peripheral condition.

Finasteride treatment directly impacts penile health by altering hormonal metabolism in the corpus cavernosum, drastically reducing local DHT levels. This change impairs the activity of the enzyme nitric oxide synthase (NOS) and decreases nitric oxide levels, elements fundamental for tissue relaxation and maintaining a firm erection… The persistence of sexual dysfunction in post-finasteride syndrome suggests that the problem may be rooted in a failure of the central nervous system’s control over sexual function, and not merely in a compromised peripheral condition.

—Analysis via Instagram: December 24, 2025